What causes pyelonephritis?

Pylonephritis is a urinary tract infection disease, which is generally divided into ascending and descending. Generally, urinary tract infection is the main cause of pyelonephritis. The incidence of pyelonephritis in women is very high. Most early pyelonephritis is asymptomatic, so it is often ignored by many people. By the time they know about it, it has reached the middle or late stage. Pylonephritis can be cured if it is treated in time and the infection is controlled.

What causes acute pyelonephritis?

1Acute pyelonephritis can be caused by blood-borne infection. For example, if an infection lesion appears somewhere in the patient's body, the bacteria that cause the disease can enter the body's blood circulation through the infection lesion, and then reach the renal pelvis of the human kidney and cause the body to become ill.

2 Ascending infection can also lead to acute pyelonephritis. This type of infection usually enters the human body through the infected lesions of urethritis or cystitis. The pathogenic bacteria can then reach the lymphatic tissue along the human ureter and enter the human body through the lymphatic circulation, even causing disease.

3 In fact, the occurrence of this disease has a lot to do with a person's body resistance, because under normal circumstances, people are not prone to acute pyelonephritis. It is only when the body's resistance mechanism is weakened that bacteria can take advantage of the situation and infect the human urinary system, and then enter the kidneys through the urethra to cause disease.

How harmful is acute pyelonephritis to the human body?

1. Patients may develop sepsis, mainly because the disease develops rapidly in the early stages, and they often have chills and high fever. In severe cases, they may even suffer from shock. At this time, patients should receive timely treatment.

2. It can cause infectious stones in patients, mainly because the urease contained in Proteus can decompose the urea in the patient's urine, making the urea alkaline. The solubility of phosphate in alkaline urine will be significantly reduced, and precipitation is easy to occur at this time, forming magnesium ammonium phosphate and apatite stones.

3. The hazards of acute pyelonephritis. Patients will also have abscesses on all sides of the kidneys. The pathogens are mostly Gram-negative bacilli, with Escherichia coli being the most common. Patients often have obvious unilateral low back pain and tenderness. The pain will worsen when the patient bends over to the healthy side. In addition, patients will suffer from femoral head necrosis, which is a serious complication that often occurs in patients with diabetes and urinary tract obstruction. In severe cases, patients will also suffer from acute renal failure.