How to choose biologics for ankylosing spondylitis?

Ankylosing spondylitis is a relatively common disease in the human body. It is a physical disease caused by lesions in the human vertebrae. Suffering from ankylosing spondylitis has a great impact on physical health. Biological agents for ankylosing spondylitis are common drugs for the treatment of ankylosing spondylitis. The selection of biological agents needs to be based on the needs of the disease. Some anti-inflammatory biological agents can be selected.

Biologics for ankylosing spondylitis

What are biologics?

Currently, the main biological agents for the treatment of ankylosing spondylitis are tumor necrosis factor-mediated

Indications for the use of biologics in ankylosing spondylitis

Nonsteroidal anti-inflammatory drugs; Treatment failure: If there is no response or intolerance to at least two different types of nonsteroidal anti-inflammatory drugs for more than 4 weeks, biologic therapy may be considered. Each NSAID should be used at the maximum tolerated therapeutic dose.

For patients with severe peripheral spondyloarthritis or axial spondyloarthritis who are unable to use biologic agents, traditional slow-acting antirheumatic drugs should be tried. If treatment fails, biologic agents can be considered.

Hip joint involvement: The disability rate of patients with obvious hip joint inflammation is particularly high. The cost of medication is much lower than the cost of joint replacement. Generally, all rheumatologists will recommend you to use biological agents. If you are not financially difficult, do not hesitate. If it is a bit difficult to bear and it only causes short-term difficulties in life, you should create conditions to use them.

Combined psoriasis, iritis and inflammatory bowel disease: For these patients, there is good evidence to prove the good effect of biological agents, and they can also be used.

Patients in the ultra-early stage have more severe symptoms of inflammation: using treatment at this time may be able to nip the disease in the bud, so it is still necessary to be proactive.

If the spine has become bamboo-like, the sacroiliac joints have become ankylosed, the hip joints have been obviously damaged, the inflammation in the MRI is no longer obvious, and the erythrocyte sedimentation rate and C-reactive protein are no longer high, then no medication will really improve the condition. The patient should consider how to exercise and how to live. Medication can be used to relieve pain, but do not use any medication that exceeds your financial ability or any treatment that is not offered by doctors in regular hospitals. Instead, save some money for future surgery.