What are the causes and hazards of low uric acid?

Uric acid is actually a product of purine metabolism in the body. Both high and low uric acid levels may have certain adverse effects on physical health. It may be caused by eating less protein foods. Renal hypouricemia and familial hypouricemia may also have symptoms of low uric acid. If it is caused by diet, you should pay attention to dietary adjustment. Low uric acid may cause chronic nephritis, hepatitis and other problems.

1. Uric acid is a product of purine metabolism in the body. When uric acid is low, it indicates a physical disease. Under normal circumstances, the uric acid level in the body is in a dynamic equilibrium state. There are many reasons for low uric acid, including improper daily life, disease induction, and genetics.

2. Low uric acid may be caused by eating less protein food, which generally has no effect on the body. I don’t know the extent of your low uric acid level, because renal hypouricemia, familial hypouricemia, multiple myeloma, alcoholic liver disorder, primary biliary cirrhosis, early stage diabetic nephropathy, and xanthine oxidase excess may all lead to low uric acid. There is no harm in having low uric acid, but it may mean that you are not consuming enough protein. Try supplementing with more protein to see if it helps. If that doesn't work, I suggest you go to the hospital for a comprehensive check-up.

3. If low uric acid is caused by diet, you can adjust your diet and then check the uric acid again to observe changes in the values. Low uric acid levels can cause chronic nephritis, hepatitis, kidney cancer and other hazards. Patients who have undergone fracture surgery may experience low uric acid levels. The serum uric acid concentration in patients with liver disease is lowered, mostly because of liver cell damage after liver disease, reduced purine synthesis or inhibition of purine oxidase activity, which cannot oxidize purine into uric acid, resulting in a lower uric acid concentration in the blood.

4. The kidney's transport of uric acid goes through four steps: glomerular filtration, proximal tubular reabsorption, secretion, and reabsorption after secretion. If the renal tubular function is damaged, the reabsorption and secretion function of the proximal tubules will decrease or increase, which will lead to a decrease in blood uric acid concentration and cause renal hypouricemia.