Will IVF babies have defects? Should I do it or not

In life, we often hear that test-tube babies may have defects. In fact, test-tube babies have become a very common disease now. The technology and medical skills related to test-tube babies have developed to a very rich stage, so the chance of defects in test-tube baby surgery is very low. Common defects include weak constitution, easy to get sick, congenital diseases, etc., which can be avoided as long as regular check-ups are done.

Because the IVF technology itself has defects, the application of this technology is also risky.

1. For example, in order to obtain more mature eggs in a few days, patients are usually given ovulation-inducing drugs, which can lead to ovarian hyperstimulation syndrome and premature ovarian failure. It may also increase the chance of eggs carrying mutant genes, and the egg retrieval process itself may cause damage to the female body.

or possibility of infection.

2. Due to the low success rate of in vitro fertilization, in order to increase the success rate of conception, most of the methods used are to implant multiple embryos at a time. But this will lead to an increase in the rate of multiple births. Multiple births increase the risk of premature birth, low birth weight, and complications for the pregnant woman. If more than one embryo develops normally after embryo implantation, the multiple birth rate can be reduced by artificially reducing the number of fetuses, but the fetal reduction process itself also has risks. A better solution is to combine embryo freezing technology with single embryo transfer. When a course of treatment is unsuccessful. Frozen embryos are retrieved for the next treatment.

3. Although there is no direct evidence that test-tube babies have a higher rate of congenital defects or differences in intellectual development than ordinary babies. But when in vitro fertilization is achieved through in vitro fertilization technology, especially ICSI technology. Increased risk of passing defective genes carried by sperm to offspring. Moreover, for those infertility caused by unknown reasons, the use of in vitro fertilization technology may make it possible. This suggests that defective genes may have a chance to be preserved and passed down throughout human genetic evolution, and the possible impact on future generations is still difficult to predict.

4. PGD technology and other technologies derived from it, such as PGS and PGH, are all based on the genetic diagnosis of a blastomere in a multicellular embryo. However, due to the existence of embryonic chromosomal mosaicism, the risk of diagnosis lies in whether the selected cell can truly reflect the characteristics of the entire embryo. False-negative results can lead to the misselection of malformed embryos, while false-positive results can lead to the rejection of normal embryos.

5. Its ethical issues have been affecting families with different ideologies and are difficult to estimate.