If a couple has not been able to get pregnant for a long time after marriage, they should go to the hospital for a check-up to see if there is an infertility problem. If the body allows, many people will choose to achieve pregnancy through in vitro fertilization. Although the price of in vitro fertilization is not low, it can increase the chance of success. The chance of success after the third generation of in vitro fertilization is very high, because our country now has relatively complete development of in vitro fertilization technology. Chromosome 13: Chromosome 13 abnormalities often occur - trisomy syndrome (Patau syndrome) with an incidence of about 1/5000. The disease is caused by an extra chromosome 13. Children with the disease have multiple malformations and most die within three years of birth. Abnormalities in chromosome 13 cause breast and ovarian cancer, deafness, liver and nervous system diseases. Chromosome 16: Familial Mediterranean fever, polycystic kidney disease (large numbers of cysts in the kidneys), and intestinal dysfunction. Chromosome 18: Chromosome 18 abnormalities often lead to trisomy syndrome (Edwards syndrome), which is a serious chromosomal abnormality with an incidence of approximately 1/6000. Patients with trisomy 18 usually present with multiple organ defects and most die within the first year of life. It often causes Niemann-Pick disease (anemia, enlarged liver, spleen, lymph nodes, indigestion and neurological defects, pancreatic cancer and other diseases. Chromosome 21: Down's syndrome Chromosome 22: The bone marrow is replaced by malignant white blood cells, resulting in chronic myeloid leukocytosis. X chromosome: Duchenne muscular dystrophy (DMD), Turner syndrome, Fragile X syndrome Y chromosome: acute myeloid leukemia The normal chromosome type for females is XX and the normal chromosome type for males is XY. Sex chromosome abnormalities are relatively common, with an incidence of about 1/500. Experts believe that about 25% of spontaneous abortions are caused by sex chromosome abnormalities. The following are three common symptoms of sex chromosome abnormalities: Turner syndrome (congenital absence of ovary syndrome) has an incidence rate of 1/10,000 in female babies and is the main cause of chromosomal abnormalities leading to miscarriage. Affected girls have only one X chromosome, 45X, instead of two. When patients grow up, they have short stature, abnormal necks, incomplete sexual development, abnormally small ovaries, and often suffer from heart and kidney diseases. These symptoms often go unnoticed until puberty. The karyotype is 45,X. |
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