Very few people know the correct treatment for metastatic lung cancer!

Metastatic lung cancer is a symptom caused by the metastasis of malignant tumors in the body to the lungs. It usually causes malignant tumors on both sides of the lungs, causing life-threatening danger. There are many treatments for metastatic lung cancer, but generally there is no special treatment. You can choose conservative treatment or surgical treatment.

Causes

Metastatic lung cancer is the metastasis of malignant tumors in other parts of the body, which can be spread by blood, lymph nodes or direct invasion of adjacent organs. Choriocarcinoma and breast cancer are the most common, followed by malignant soft tissue tumors, liver cancer, osteosarcoma and pancreatic cancer; there are also thyroid cancer, kidney cancer, prostate cancer, etc.

Hematogenous metastasis is the most common form of pulmonary metastasis, in which tumor cells flow back to the right heart through the vena cava and then metastasize to the lungs. Lymphatic metastasis usually spreads through the bloodstream to the pulmonary arterioles and capillary beds, and then penetrates the blood vessel walls to invade the peribronchial lymph nodes. It often occurs in the interstitium around bronchovascular vessels, interlobular septa, and subpleural interstitium, and spreads to the lungs through lymphatic vessels. The primary disease that causes direct metastasis of the tumor to the lung is a malignant tumor of the pleura, chest wall, and mediastinum.

treat

Surgery, chemotherapy, and radiation therapy are the three main treatments for metastatic lung cancer. The choice of treatment depends on the status of the primary tumor, the type, location, and number of metastatic lung cancer, and the patient's general condition. Surgical treatment is the first choice for the treatment of metastatic lung cancer and is currently the standard treatment for metastatic lung cancer. If there is no metastasis to other parts of the body, pulmonary metastases resection can achieve a radical cure. Many tumors are not sensitive to chemotherapy and radiotherapy, such as soft tissue sarcoma lung metastasis, and surgery is the most important treatment method. From an economic perspective, the cost-effectiveness ratio of surgery is also higher. Among patients who meet surgical criteria, more than one-third are expected to achieve long-term survival (>5 years). A solitary pulmonary metastatic nodule does not necessarily represent the terminal stage of a systemic or incurable primary malignancy. The surgical conditions that patients need to meet for lung resection of metastatic lung cancer include control of the primary tumor, complete resection of all metastases, absence of extrathoracic metastases, and sufficient cardiopulmonary function to tolerate the surgery. For patients with metastatic lung cancer, controlling the primary cancer, excluding extrathoracic metastasis, and completely removing all palpable metastases means prolonging survival. Pulmonary resection for metastatic lung cancer can also be used for restaging, prognosis, and guidance of further treatment.

In a few cases, there is only a single metastatic nodule in the lung, or there are several metastatic lesions but they are all limited to one lobe or one side of the lung. If the primary tumor has been controlled after treatment, there is no local recurrence, and no other metastatic lesions are found in other parts of the body after various examinations, and the general condition can withstand lung resection, surgical treatment should be considered. However, the extent of lung resection should be as conservative as possible, usually only wedge or segmental lobectomy. After surgery, appropriate anti-tumor drug treatment was given according to the pathological diagnosis of the tumor. In some cases, new isolated metastatic lesions may appear in the lungs several months or years after the resection of metastatic lesions. As long as there is no metastasis to other organs and tissues, lung resection can be performed again.

For patients with multiple metastatic lung cancer in both lungs, if the primary tumor has been controlled after treatment, there is no local recurrence, and no other metastatic lesions are found in other parts of the body after various examinations, and the patient's general condition can withstand lung resection, local resection of metastatic lung cancer in both lungs through sternotomy, local resection of metastatic lung cancer in both lungs through simultaneous thoracoscopic surgery, or/and local resection of metastatic lung cancer by staged bilateral thoracotomy can be considered.

Chemotherapy has limited efficacy in metastatic lung cancer. The principle of chemotherapy is to choose the same chemotherapy drugs as those used to treat the primary tumor.

Radiation therapy is more sensitive to Wilms tumor, Ewing sarcoma and germ cell metastatic lung cancer, and can be given to single metastatic lung cancer in one or both lungs.