How to treat lung cancer metastasis

Lung cancer is a symptom caused by lesions in the human lungs. Generally, symptoms of lung cancer metastasis are prone to occur in the late stage of lung cancer. It usually metastasizes to the brain or bones, etc., causing great pain to the patient and endangering his life. Drug treatment can be carried out according to the severity of the disease.

Treatment

1. Treatment of brain metastasis of lung cancer:

Lung cancer is the most common tumor with intracranial metastasis. When patients experience symptoms such as headache, vomiting, limb weakness, mental abnormalities, vision changes, and movement disorders, they must be highly vigilant and undergo brain CT and MRI examinations to determine whether brain metastasis has occurred in order to buy time for treatment. Once brain metastasis is confirmed, it must be treated immediately. Dehydration treatment is the most commonly used symptomatic treatment method. If fundamental treatment is desired, radiotherapy combined with traditional Chinese medicine or radiotherapy combined with biological therapy is often used clinically, and the effect is better than radiotherapy alone.

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2. Treatment of liver metastasis of lung cancer:

The liver is also a common site of metastasis of lung cancer, and about 30% of lung cancer patients will experience liver metastasis. The most common symptom of liver metastasis is persistent pain in the liver area, accompanied by loss of appetite and indigestion. For isolated metastatic lesions in the liver, surgery can be used to relieve symptoms, but it still depends on the specific situation of the patient. Biological immunotherapy can be used to relieve pain.

3. Treatment of bone metastasis of lung cancer:

About 50% of lung cancer patients will eventually develop bone metastases in multiple locations, most commonly in the ipsilateral ribs and spine. There are no symptoms in the early stages of bone metastasis, but in the late stages it manifests as local, persistent pain with fixed tender points. The most terrifying thing after bone metastasis occurs is that once the tumor metastasizes to the body's weight-bearing bones such as the cervical vertebrae, thoracic vertebrae, and lumbar vertebrae. It may cause serious consequences such as paralysis. In addition, bone metastasis can also lead to osteolysis, hypercalcemia and pathological fractures, seriously reducing the patient's quality of life. Patients can receive comprehensive treatment with chemotherapy or radiotherapy combined with biological immunotherapy, which has better effects than radiotherapy and chemotherapy alone.

Lung cancer metastasis

1. Brain metastasis

Why is lung cancer prone to brain metastasis? This is because there are a large number of anastomoses between the cerebral blood vessels and the vertebral arteries and venous arterial plexus that supply the brain, which allows lung cancer cells to bypass the filtration of the pulmonary capillaries and metastasize directly to the brain through the heart and carotid arteries. According to clinical data analysis, if one of the following situations occurs, one should be highly alert to the possibility that lung cancer has just begun to metastasize to the brain or has already metastasized to the brain.

Bone Metastasis

Approximately 50% of lung cancer patients will eventually develop bone metastases in multiple locations. There are generally no symptoms in the early stages of bone metastasis, but bone isotope scanning can reveal diseased bones. The symptoms of bone metastasis are related to the location and number of tumor metastases. For example, chest pain caused by rib metastasis of lung cancer is often manifested as pain localized in the chest wall with clear tenderness points. Spinal cord metastases cause pain in the middle or lesion area of ​​the back, while bone metastases in the limbs or trunk cause localized pain in that area. Bone metastasis is not a direct cause of threat to the life of lung cancer patients, but if the tumor metastasizes to the body's weight-bearing bones such as the cervical vertebrae, thoracic vertebrae, lumbar vertebrae, etc., it can cause serious consequences such as paralysis. Therefore, patients with lung cancer and bone metastasis should be treated promptly.

1. Characteristics of lung cancer bone metastasis:

Bone is the most common site of metastasis of lung cancer, especially small cell lung cancer and poorly differentiated non-small cell lung cancer, with an incidence of 30% to 70%. It often occurs in the axial skeleton, mainly the spine, ribs and pelvic bones, and is less common in the limbs. There are no clinical symptoms in the early stage of bone metastasis, but pain appears in the late stage, mainly manifested as local pain and joint dysfunction in the affected bones, while respiratory symptoms are mild or absent, which is very easy to misdiagnose clinically. It often takes more than a year from the occurrence of bone metastasis to the onset of clinical pain. Therefore, lung cancer patients should not refuse clinical examinations and exclude symptoms of bone metastasis simply because they have no pain symptoms. Cancerous bone pain is characterized by fixed location, gradually increasing pain, and is more obvious at night; thoracic metastasis will produce band-like pain; lumbar metastasis often causes radiating pain along the outside of the lower limb to the outside of the foot, which worsens with activities such as coughing and defecation. Sciatica that resembles bone hyperplasia or disc herniation should be treated with caution.

Since bone metastases from lung cancer are mostly osteolytic lesions, pathological fractures and hypercalcemia may sometimes occur. The most commonly used examination in clinical practice is isotope bone scanning, which can quickly display systemic bone metastasis and has high sensitivity but low specificity. MRI and CT can display local bone metastases, so their specificity and local positioning are better than bone scanning, especially local MRI is superior to CT. X-rays have low sensitivity and can only show osteolytic lesions when they are larger than 1 cm. However, since it still has its advantages for flat bones and is inexpensive, X-rays of these areas are still a commonly used examination method.