What are the symptoms of lymphoma?

There are lymph nodes in the human body. The lymph nodes are mainly distributed in the neck, including the upper body. The lymphatic circulation in the upper body will promote detoxification. The continuous circulation of the lymph nodes helps the human body purify toxins. Therefore, the lymph nodes can easily get sick because there are too many toxins accumulated in them. Once a lymph node tumor occurs, the patient will have symptoms such as difficulty breathing, uncomfortable symptoms in the body, mild fever and pain, and severe cases will be accompanied by loss of appetite and night sweats.

1. The disease originates in lymph nodes and lymphoid tissue.

Superficial lymph nodes are the most common sites of disease, and HD is more common than NHL. The most affected lymph nodes are in the neck, followed by the armpits and groin. It is generally painless, progressively enlarged, and of medium hardness. In the early stage, the lymph nodes are movable, but in the late stage, adhesions and multiple swollen lymph nodes often fuse into masses. In some HD patients, lymph node enlargement may temporarily stop or even shrink at a certain time, leading to misdiagnosis of lymphadenitis or lymphadenopathy.

The disease starts in the deep lymph nodes, most commonly the mediastinal lymph nodes. The enlarged lymph nodes can compress the superior vena cava, causing superior vena cava syndrome. It can also compress the trachea, esophagus, and recurrent laryngeal nerve, causing symptoms such as dyspnea, dysphagia, and hoarseness. Mediastinal NHL is more common with concurrent lymphosarcoma cell leukemia. Young women who first develop HD in the mediastinum are often of the tuberous sclerosis type and often respond unsatisfactorily to treatment.

Malignant lymphoma originating in the retroperitoneal lymph nodes, most commonly NHL, can cause long-term, unexplained fever, making clinical diagnosis difficult.

Lymphoma that first arises in the pharyngeal lymphatic ring is more common in NHL and is often accompanied by subdiaphragmatic invasion. Symptoms include sore throat, foreign body sensation, shortness of breath and hoarseness.

2. The disease occurs outside the nodule.

Except for lymphatic tissue, the disease can occur in any part of the body, among which the gastrointestinal tract is the most common. Stomach and high small intestinal lymphoma may have symptoms such as upper abdominal pain and vomiting. Small intestinal lymphoma often occurs in the ileocecal region, often with chronic diarrhea, steatorrhea, and intestinal obstruction.

3. Systemic symptoms.

Common symptoms include general weakness, weight loss, loss of appetite, night sweats and irregular fever. A small number of HD patients may have periodic fever.