Is duodenal bulb ulcer serious? How should it be treated?

Most duodenal ulcers occur in the duodenal bulb cavity, causing varying degrees of ulcers in the internal mucosal muscular layer. There will be bleeding at the ulcer site, and in severe cases the bleeding will be more severe, posing a direct threat to life, so early treatment is needed.

treat

1. Medication

The goals are to control symptoms, promote ulcer healing, prevent recurrence, and avoid complications. The most commonly used drugs are divided into the following categories:

(1) Drugs that inhibit gastric acid secretion

Currently, the main clinical drugs include H2 receptor antagonists (H2-RA) and proton pump inhibitors (PPI). PPI promotes ulcer healing faster and with a higher healing rate, and is the first choice for the treatment of duodenal ulcers. Commonly used PPIs include omeprazole, pantoprazole, lansoprazole, rabeprazole, esomeprazole, and ilaprazole.

(2) The combined use of mucosal protective agents and gastric acid inhibitors can improve the quality of ulcer healing and reduce ulcer recurrence.

(3) Gastrointestinal prokinetic drugs are mainly used for patients with symptoms such as nausea, vomiting, and abdominal distension to promote gastrointestinal emptying and relieve symptoms.

(4) Eradication of Helicobacter pylori

2. Surgery

Mainly used to treat complications (perforation, bleeding, obstruction).