The significance of glycosylated hemoglobin

The detection of glycosylated hemoglobin has attracted increasing clinical attention. By detecting glycosylated hemoglobin, we can understand the average blood sugar level within three months. Therefore, the detection of glycosylated hemoglobin has great clinical significance. Understanding its characteristics has great clinical value in preventing and treating diabetes.

The characteristics of glycosylated hemoglobin determine its great significance in diabetes monitoring:

(1) Parallel to blood sugar levels. The higher the blood sugar, the higher the glycated hemoglobin, so it can reflect the level of blood sugar control.

(2) Slow generation. Since blood sugar is constantly fluctuating, each blood draw can only reflect the blood sugar level at that time, while glycosylated hemoglobin is gradually produced. A short-term increase in blood sugar will not cause an increase in glycosylated hemoglobin; conversely, a short-term decrease in blood sugar will not cause a decrease in glycosylated hemoglobin. Since eating does not affect the measurement, it can be measured after a meal.

(3) Once formed, it is difficult to decompose. Glycated hemoglobin is quite stable and not easy to decompose. Therefore, although it cannot reflect short-term blood sugar fluctuations, it can well reflect the degree of blood sugar control over a longer period of time. Glycated hemoglobin can reflect the average blood sugar level within 2 months before blood collection.

(4) Less affected by hemoglobin levels. Glycated hemoglobin refers to its ratio in total hemoglobin and is therefore not affected by hemoglobin levels.