Can chronic hepatitis patients be cured?

In order to achieve better results in the treatment of chronic hepatitis, the choice of methods should focus on common liver protection treatments, including the use of some drugs, such as glycyrrhizic acid preparations and Schisandra preparations, but the use of drugs and contraindications of taking drugs should also be understood.

① Liver protection treatment: There are many types of drugs, including glycyrrhizic acid preparations, silymarin preparations, schisandra preparations, etc.

Applicable to all patients with chronic hepatitis.

② Anti-fibrosis treatment: mostly oral preparations of Chinese patent medicines, also suitable for all chronic hepatitis patients.

③Injection of interferon antiviral treatment: (2a and 2b), suitable for patients with chronic hepatitis B and chronic hepatitis C, with a treatment course of at least 1 year. Interferon combined with ribavirin is the standard treatment for chronic hepatitis C. The efficacy depends on the HCV genotype and the speed of response to treatment. Those whose HCV levels fall below the detection line within 4 weeks of treatment (commonly known as negative conversion) are called rapid responders (RVR). This group of people respond best to interferon treatment, with a cure rate of 87%. (2a, 2b and 1b) and pegylated interferon including regular interferon.

④ Oral nucleoside analog antiviral therapy: This type of drug is only suitable for the treatment of hepatitis B, including chronic hepatitis B and hepatitis B cirrhosis. There are four drugs available in mainland China: lamivudine (LAM), adefovir dipivoxil (ADV), telbivudine (LdT), and entecavir (ETV); there is also a fifth drug available internationally: tenofovir disoproxil fumarate (TDF), which is used to treat patients who are resistant to the above four drugs. The advantages of nucleoside analogs are good antiviral efficacy, few side effects, and easy to take, one tablet per day. They are widely used in clinical practice, prolonging the survival of patients with cirrhosis and significantly improving their quality of life. The disadvantage is that it needs to be taken for a long time and there is a risk of drug resistance. As a special medicine for the treatment of chronic hepatitis B, it must be used under the guidance of a doctor, and the hepatitis B virus quantification needs to be checked regularly. If you take or stop taking the medicine at will, it will promote the occurrence of hepatitis B virus resistance and worsen the disease, and even lead to death.

⑤ Immunosuppressants: When autoimmune hepatitis recurs and liver function is difficult to control with liver protection drugs, if liver biopsy indicates obvious intrahepatic inflammatory activity, glucocorticoids need to be used, or another immunosuppressant azathioprine can be used in combination to promote recovery of the disease.