What is the purpose and method of vasodilation

In daily life, as people's stress increases, various diseases have caused us great trouble. These diseases make us feel depressed and unable to concentrate. Some diseases seriously affect our physical health and sleep quality, while some diseases threaten our lives. So we're all looking for solutions. What is the purpose and method of vasodilation?

Objective: To detect the vascular endothelial cell function of the brachial artery in normal non-pregnant, early, mid-pregnant, and late-pregnant women of childbearing age and women with pregnancy-induced hypertension and gestational diabetes in late pregnancy using flow-mediated vasodilation technology, to discover and explore the changes in vascular endothelial function in normal women at different stages of pregnancy and women with hypertension and diabetes during pregnancy; to analyze the significance and value of FMD in evaluating vascular endothelial function in normal pregnancy and pregnancy with hypertension and gestational diabetes, so as to provide parameter support for clinical diagnosis and treatment.

Methods: Color Doppler ultrasound diagnostic instrument equipped with linear array probe with frequency of 7.0-12.0MHz was used to detect brachial artery in 32 non-pregnant women of childbearing age (15 of whom were repeatedly measured at different times by the same operator), 77 early pregnant women, 40 mid-pregnant women, and 73 late pregnant women (including 38 normal late pregnant women, 20 pregnant women with hypertension during pregnancy, and 15 pregnant women with diabetes during pregnancy) who visited our hospital from March 2012 to March 2014. The changing characteristics of FMD-related parameters in normal non-pregnant women of childbearing age, early pregnant women, mid-pregnant women, and late pregnant women were compared, as well as the changing characteristics of FMD-related parameters in normal late pregnant women and pregnant women with hypertension complication during pregnancy and gestational diabetes.

The results were statistically processed, and P < 0.05 was considered statistically significant. result:

1. The brachial artery FMD values ​​were significantly consistent when the same operator performed repeated measurements on the subjects. There was no statistically significant difference between repeated FMD measurements of subjects by the same operator.

2. The FMD values ​​of the brachial artery of normal non-pregnant, early pregnancy, mid-pregnancy, and late pregnancy groups are as follows: the mean ± standard deviation of the FMD of the brachial artery of normal non-pregnant women of childbearing age is 7.66±2.74%; the mean ± standard deviation of the FMD of the brachial artery of early, mid-pregnant, and late pregnant women are 11.06±3.74%, 9.32±3.61%, and 8.26±3.13%, respectively. The FMD in early, middle and late pregnancy increased by 44.39%, 21.67% and 7.83% respectively compared with the non-pregnancy period. There were significant differences in FMD values ​​between the early pregnancy group and the non-pregnancy group, the second pregnancy group, the third pregnancy group, and between the non-pregnancy group and the second pregnancy group (P < 0.05); there were no significant differences in FMD values ​​between the other groups (non-pregnancy group and the third pregnancy group, the second pregnancy group and the third pregnancy group) (P > 0.05).

3. The mean ± standard deviation of brachial artery FMD in pregnant women with gestational hypertension in late pregnancy was 5.94±3.75%. There was a significant difference in FMD between the normal group in late pregnancy and the gestational hypertension group (t=2.51, P<0.05). The mean ± standard deviation of brachial artery FMD in pregnant women with gestational diabetes was 5.83 ± 3.81%. There was a significant difference in FMD between the normal group in late pregnancy and the gestational diabetes group (t=2.39, P0.05). However, there was no significant difference in FMD values ​​between the third trimester hypertensive disorders complication of pregnancy and gestational diabetes mellitus (t=0.08, P>0.05). The FMD values ​​of 7.40% and 7.39% were used as the thresholds for diagnosing third trimester hypertensive disorders complication of pregnancy and gestational diabetes mellitus, and the areas under the curves were 0.71 and 0.73, respectively.

After reading the above introduction to the purpose and methods of vasodilation, I think everyone should have understood it. There are many methods of vasodilation. We must correctly understand and master the knowledge of the disease, and take corresponding measures according to its symptoms to carry out targeted improvement and treatment. We must pay attention to our health and protect it well.