Treatment and causes of thyroid adenoma

The incidence of thyroid tumors in our country is still relatively high, so this disease has attracted the attention of many departments in our country. It is believed that the development of this disease will pose a threat to the health of many people. Therefore, many patients with this disease want to know its treatment methods and causes. In order for you to understand it as soon as possible, please take a look at the following answers.

treat

Treatment selection is based on clinical manifestations and patient preferences, and close observation or surgical treatment may be chosen.

Causes

The cause of thyroid adenoma is unknown, but it may be related to gender, genetic factors, radiation exposure, TSH overstimulation, and endemic goiter.

1. Gender

The incidence of thyroid adenoma in women is 5 to 6 times that in men, suggesting that gender factors may be related to the onset of the disease.

2. Oncogenes

The expression of oncogene c-myc can be found in thyroid adenomas. Activating mutations and overexpression of the oncogene H-ras can also be found in adenomas. Mutations of proteins involved in the TSH-G protein adenylyl cyclase signaling pathway can also be found in high-functioning adenomas, including mutations in the extracellular and transmembrane segments of the TSH receptor transmembrane functional region and mutations in the stimulatory GTP-binding protein.

3. Familial tumor syndrome

Thyroid adenomas may be seen in some familial tumor syndromes, including Cowden disease and Catney syndrome.

4. External radiation exposure

The incidence of thyroid tumors is also increased in people who have undergone X-ray treatment of the head, neck, and chest during childhood.

5. TSH Overstimulation

Some patients with thyroid adenoma may be found to have elevated blood TSH levels, which may be related to the onset of the disease. Experiments have found that TSH can stimulate normal thyroid cells to express the pro-oncogene c-myc, thereby promoting cell proliferation.

The above content has comprehensively explained the treatment methods and causes of thyroid tumors. Many patients with this disease must not ignore the harm it brings to themselves. They should understand the above content, undergo comprehensive examinations, and receive effective treatment as soon as possible so that they can recover as soon as possible.