Causes of osteosarcoma

Before introducing the causes of osteosarcoma, let's take a look at what osteosarcoma is. Osteosarcoma, also known as osteogenic sarcoma, is a malignant bone tumor that often occurs in adolescents or children under the age of 20. Osteosarcoma develops from the mesenchymal cell line. Because the tumor directly or indirectly forms tumor bone-like tissue and bone tissue during the cartilage stage, the tumor grows rapidly. After understanding what osteosarcoma is, let's take a look at the causes of osteosarcoma.

Osteosarcoma is the most common type of malignant bone tumor. It develops from the mesenchymal cell line. The rapid growth of the tumor is due to the direct or indirect formation of tumor bone-like tissue and bone tissue through the cartilage stage. Under the influence of external factors (such as viruses), the weight-bearing bones of the lower limbs cause cell mutations, which may be related to the formation of osteosarcoma.

Typical osteosarcomas originate from the bone, while another completely different type of osteosarcoma is the osteosarcoma that is parallel to the bone cortex and originates from the periosteum and nearby connective tissue. The latter is less common and has a slightly better prognosis.

In addition, it is related to heredity, exposure to radioactive substances, viral infection, etc. It can also be secondary to osteitis deformans and fibrous dysplasia of bone. Some cases are caused by the malignant transformation of other benign tumors.

Osteosarcoma is a major tumor disease in orthopedics. If it is not treated in time, it will seriously endanger the patient's life, especially in children and adolescents. Therefore, it is very important to understand the causes of osteosarcoma and prevent it early.

To sum up, after we have a detailed understanding of the causes of osteosarcoma, we can reduce the occurrence of osteosarcoma by taking more precautions in our daily work and life.