Early treatment methods for teratoma

Ovarian teratoma is a congenital tumor, mostly formed by the ectopic development of some multipolar differentiated cells during embryonic development. It contains three germ layers of tissue, and histologically, multiple tissues and cells are seen. It can be divided into two categories: dermoid cysts (cystic ovarian teratoma) and ovarian teratoma. The tumor can become malignant, malignant ovarian teratoma. Tumors are mostly found in young or middle-aged people, so what is the early treatment method for teratoma? Let's listen to the experts' introduction below.

Treatment of ovarian teratoma (I) Ovarian teratoma can be tested for tumor anti-cancer. If pathological examination is required, you should apply for frozen sections to avoid secondary surgery.

Treatment of ovarian teratoma (II) After surgery for ovarian teratoma, pregnancy can be achieved as long as normal ovarian function is restored. After the teratoma is diagnosed, it is best to perform surgery as soon as possible to treat the ovarian teratoma.

Treatment of Ovarian Teratoma (III) Teratomas can be divided into benign and malignant types, but malignant teratomas are different from other ovarian malignant tumors. Teratomas are formed by another embryo during fetal development and do not belong to the patient's own tissue. Neither benign nor malignant represents the nature of the patient's own ovarian tissue. As long as the surgery is delicate and the technique is sophisticated, the teratoma can be completely separated and the patient's own ovarian tissue can be retained. Therefore, in the treatment of ovarian teratoma, no matter whether the teratoma is benign or malignant, it is not necessary to remove the ovaries.

Among the treatment methods for ovarian teratoma, laparotomy is limited by the incision, has a small field of view, and is difficult to operate. It is often not easy to remove the teratoma tissue cleanly. Laparoscopic surgery has a wide field of view and a magnifying effect, which can completely remove the teratoma tissue without contaminating the abdominal cavity. At the same time, it is convenient to explore the contralateral ovary (more than 50% of teratomas are bilateral and occur successively). Therefore, ovarian teratoma is treated with laparoscopic surgery without laparotomy.

For patients with large or extensively infiltrated malignant teratomas that are clinically judged to be unresectable, preoperative chemotherapy or radiotherapy can be used to shrink the tumor before delayed radical surgery, which is of positive significance in improving the surgical resection rate and preserving important organs. For advanced cases, preoperative chemotherapy or radiotherapy can also achieve the therapeutic goal of relieving tumor compression, controlling metastatic lesions, and gaining the opportunity for reoperation.

Ovarian teratomas are generally asymptomatic clinically, but may cause abdominal distension, mild abdominal pain and compression symptoms when they grow up. The contents of teratomas are composed of a variety of mature tissues from 2 to 3 germ layers, most of which are ectoderm tissues. Therefore, squamous epithelium, sebaceous glands, sweat glands, hair and mature nerve tissue, as well as mesoderm fat cartilage and bone tissue can be seen in the cyst. About half of ovarian dermoid cysts contain teeth.

Generally speaking, the prognosis of immature teratoma is poor in surgery. Surgery cannot completely and cleanly eliminate it, and there is a risk of recurrence. However, the prognosis of benign teratoma is better. The possibility of malignant transformation is only 2%-3%, and it does not affect ovarian function. After surgery, menstruation is normal, the pregnancy rate is normal, and there is no problem of recurrence.