How to diagnose melanoma? Melanoma is a skin disease that we often encounter. Knowing more about melanoma is helpful for the prevention and treatment of melanoma. So, how to diagnose melanoma? Let's answer it together. Diagnosis: Melanoma diagnosis is generally not difficult, and a few atypical cases need to be confirmed by pathological examination. Indirect immunofluorescence labeling of melanin tissue, double PAP immunoenzyme labeling assay and pigmentogen examination are helpful for diagnosis, and are helpful for the diagnosis of "non-pigmented" or oligo-pigmented melanoma and for distinguishing benign nevus cell tumors and whether they have become malignant. Laboratory tests: 1. Anti-human melanoma serum is used for indirect immunofluorescence labeling of melanin tissue. When the antiserum is diluted to 1:2, the highest positive rate can reach 89%. 2. Using Vacca double PAP immunoenzyme labeling method, when the antiserum dilution was 1:400, 82.14% showed a positive reaction. 3. Pigmentogen test: Melanogen is oxidized after being excreted by the kidneys, making the urine dark brown, which is called black urine. If ferric chloride, potassium dichromate, and sulfuric acid are added to the urine, its oxidation can be promoted. If sodium nitrate is added, the urine will be purple; if acetic acid is added first and then sodium hydroxide is added, the urine will be blue. Through the above introduction about melanoma, we melanoma patients can clearly understand the effective diagnostic methods of melanoma. In addition, when patients find that they have melanoma, they should treat the melanoma in time and maintain a good attitude. |
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