What are the symptoms of gallbladder cancer

The symptoms of gallbladder cancer are generally manifested as follows: Digestive tract symptoms: Most patients experience indigestion, aversion to greasy food, belching, and decreased appetite, which is due to gallbladder dysfunction and inability to digest fatty substances. Right upper abdominal pain: Most patients have gallstones and thus present similar symptoms to gallstone cholecystitis, with discomfort in the right upper abdomen followed by persistent dull pain or dull pain, sometimes accompanied by paroxysmal severe pain radiating to the right shoulder.

Right upper abdominal mass: About half of the patients have a mass in the right upper abdomen or upper abdomen, most of which are enlarged gallbladders. Jaundice and skin itching: They often appear in the late stage of the disease, due to the invasion of bile duct by cancerous tissue or the compression of bile duct by metastatic lymph nodes, causing bile duct obstruction. The bile secreted by the liver cannot be discharged smoothly into the intestine, and then refluxes into the blood, showing yellowing of the skin and mucous membranes, most of which are accompanied by difficult-to-relieve skin itching, especially at night. Fever and weight loss: Some patients have fever, mostly due to secondary bile duct infection. Late-stage patients are often accompanied by weight loss and even cachexia.

Right upper abdominal mass: A relatively smooth and enlarged gallbladder can be felt in the right upper abdomen. When there is no adhesion to the surrounding tissue, it is highly mobile. When there is adhesion to the surrounding tissue, several masses can be felt, and sometimes an enlarged liver or a mass of duodenal obstruction can be felt. In nearly half of the cases, a mass can be felt in the gallbladder area of ​​the right upper abdomen at the initial diagnosis. Some parts are hard and have a nodular feel. This mass is the gallbladder. Occasionally, due to obstruction of the cystic duct, the gallbladder may have water accumulation or abscess formation, and tenderness and rebound pain in the gallbladder area may occur. Its signs are very similar to those of acute cholecystitis or obstructive cholangitis. Jaundice manifests itself in yellowing of the mucosa and skin. The yellowing is more severe and is mostly obstructive. Once jaundice occurs, the gallbladder cancer lesions are mostly in the late stage. Signs caused by metastasis: In some cases of gallbladder cancer, metastatic lymph nodes can be felt above the clavicle, and metastatic masses in the breast and other places may also appear. In advanced cases, portal vein compression may cause gastrointestinal bleeding, ascites, and liver failure. Emaciation: Most cases of gallbladder cancer show gradual emaciation, weight loss, fatigue, and cachexia.