The incidence of pancreatic cancer is related to the following factors

The incidence of pancreatic cancer is getting higher and higher, causing great harm to the patient's body. So what are the causes of pancreatic cancer ? The following is a detailed answer from relevant experts.

1. Smoking A large number of studies support the close connection between pancreatic cancer and smoking. Possible mechanisms of smoking causing pancreatic cancer: ① Smoking promotes the secretion of tobacco-specific N-nitrite, a carcinogen, into the bile duct, which then flows back into the pancreatic duct; ② The specific effect of tobacco-specific N-nitrite on organs can flow into the pancreas with the blood; ③ Smoking increases blood lipid levels and promotes pancreatic cancer.

2. Experimental studies on diabetes have shown that insulin can promote the growth of pancreatic cancer cells in vitro or in vivo; high concentrations of insulin can activate the insulin-like growth factor-1 receptor, producing growth-promoting effects including changes in cell cycle progression. This is one of the causes of pancreatic cancer.

3. Most studies on the epidemiology and molecular epidemiology of chronic pancreatitis support that chronic pancreatitis can develop into pancreatic cancer.

4. Helicobacter pylori (Hp) studies have shown that Hp serum is positive in pancreatic cancer patients, which is significantly different from the control group, suggesting that Hp infection is related to pancreatic cancer.

The above is an introduction to the causes of pancreatic cancer. I believe everyone should have a certain understanding of pancreatic cancer. If you want to know more about pancreatic cancer, please consult online experts.