Schistosoma japonicum is one of the main causes of colorectal cancer

As a common digestive system tumor, colorectal cancer has a variety of causes. Recent scientific research has found that the incidence of colorectal cancer is much higher in areas where schistosomiasis is prevalent than in other areas, so schistosomiasis is also speculated to be one of the main causes of colorectal cancer . Let's take a look at the basis for this inference.

The lesions of schistosomiasis are mainly caused by worm eggs. It is generally believed that because schistosomiasis eggs can be deposited on the colon mucosa for a long time, the intestinal mucosa is repeatedly damaged and repaired through continuous mechanical or chemical stimulation, causing local erosion, ulcers, chronic inflammation and other lesions. These chronic colon inflammations may cause granulomas, fibrosis, inflammatory polyps and adenomatous hyperplasia. Due to various factors, epithelial hyperplasia is active and eventually evolves into cancer.

Will all schistosomiasis patients eventually develop colorectal cancer? No. Although there are many signs that schistosomiasis may be one of the causes of colorectal cancer, many studies have found that the incidence of colorectal cancer in schistosomiasis-endemic areas is not significantly different from that in other areas. This may be related to people's eating habits and living standards in recent years. Some studies have reported that when patients with chronic schistosomiasis have colorectal mucosal cells, there is no significant change in the DNA content (if there is aneuploidy in the cell DNA, it is very valuable in predicting the malignant transformation of the cells), so it fails to support the direct causal relationship between schistosomiasis and colorectal cancer.

The causes of colorectal cancer caused by schistosomiasis. There are many causes of colorectal cancer. Schistosomiasis enteropathy, as a chronic irritation of the intestine, may be a precancerous lesion of colorectal cancer. Therefore, in order to prevent the occurrence of colorectal cancer, it is still very necessary to actively prevent and treat schistosomiasis. In particular, patients with schistosomiasis enteropathy should pay enough attention. If the symptoms occur frequently and are difficult to relieve, the possibility of colorectal cancer should be considered. They should go to the hospital for examination as soon as possible for digital rectal examination and colonoscopy, etc., to avoid missed diagnosis and misdiagnosis.

Dear readers, we must not ignore schistosomiasis, the main cause of colorectal cancer. We must raise our awareness of disease prevention and diagnosis in our daily lives and actively respond to colorectal cancer from all aspects to effectively protect our own health.

For more information, please visit the colorectal cancer topic at http://www..com.cn/zhongliu/ca/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.