Is rabies immunoglobulin safe?

Normally, animals need to be vaccinated against rabies, and most animals carry viruses and bacteria in their bodies. If people are accidentally bitten by small animals, it is very dangerous if the animal has not been vaccinated against rabies. Therefore, it is still important to pay attention to giving animals rabies vaccines in a timely manner. However, people should still pay attention to safety when receiving rabies vaccination. Because the human body's structure is complex, is rabies immunoglobulin safe?

Vaccination with human rabies immunoglobulin and rabies vaccine is an important measure to prevent the disease in people who are severely bitten by dogs. Rabies, commonly known as "mad dog disease", is a zoonotic central nervous system infectious disease caused by the rabies virus. The main clinical manifestations are hydrophobia, photophobia, dysphagia, mania, etc. It is the only acute infectious disease in humans with a mortality rate of up to 100%. The "Law of the People's Republic of China on the Prevention and Control of Infectious Diseases" lists rabies as a Class B infectious disease. Human rabies immunoglobulin is mainly used for passive immunization of patients bitten or scratched by rabid dogs or other mad animals.

Pharmacological Action

This product is a high-titer rabies antibody that can specifically neutralize the rabies virus and play a passive immunization role.

Indications

It is mainly used for passive immunization of patients bitten or scratched by rabid dogs or other crazy animals.

Dosage

Usage: After timely and thorough debridement, use 1/2 of the total dose of this product for subcutaneous infiltration injection at the injured area, and the remaining 1/2 for intramuscular injection (for those bitten on the head, it can be injected into the back muscles).

Dosage: The injection dose is calculated as 20 IU/kg body weight (or follow the doctor's advice), one injection. If the required total dose is greater than 10 ml, it can be injected in multiple times within 1 to 2 days. The rabies vaccine can then be injected, but the injection sites and instruments of the two products must be strictly separated.

Adverse Reactions

There are generally no adverse reactions. A few people may experience redness, swelling and pain, which do not require special treatment and can recover on their own.

Taboo

Those who are allergic to human immunoglobulin or have a history of other severe allergies.

Precautions

1. This product must not be used for intravenous injection.

2. No allergy test is required for intramuscular injection of this product.

3. Do not use if there is foreign matter or sediment that cannot be shaken off, or if the ampoule is cracked or expired.

Pregnant and lactating women

There is no research data on the effects of this product on animal reproduction. It is not clear whether the use of this product will affect reproductive capacity and whether the use of this product by pregnant women will affect the fetus. Pregnant women can only use this product when it is necessary.

Children's medication

The safety and effectiveness of this product in children have not been established. Please follow your doctor's advice when necessary.

Medication for the elderly

There is no special medication for elderly patients. Please follow the doctor's advice when necessary.

Drug interactions

1. After initiation of therapeutic vaccination, re-administration of rabies immunoglobulin is no longer recommended because it will prevent full expression of active immunity.

2. After using this product, you cannot receive live virus vaccines such as measles within three months. Because antibodies interfere with the vaccine immune response.

Pharmacology and Toxicology

Pharmacological action: This product is a high titer rabies antibody that can specifically neutralize rabies virus and play a passive immunization role.

Toxicology studies: Not clear yet