Hormone drugs are a type of drug that is widely used in clinical medicine. Many people choose to take hormones to cure the disease after they develop some health problems. However, although hormone drugs have good therapeutic effects, if taken for a long time, they will cause problems such as obesity. In addition to obesity, it can also cause metabolic disorders in the human body, induce infection, or cause some mental symptoms! 1. Cause metabolic disorders Long-term use of large doses of corticosteroids can cause disorders in the metabolism of water, salt, sugar, protein and fat: manifested as centripetal obesity, moon-shaped face, hirsutism, weakness, hypokalemia, edema, hypertension, diabetes, etc., which is clinically called Cushing's syndrome. These symptoms do not require special treatment and will generally disappear gradually on their own after stopping the medication, and will return to normal after several months or longer. If necessary, antihypertensive and hypoglycemic drugs can be used, and symptomatic treatments such as a low-blood pressure, low-sugar, high-protein diet and potassium supplementation can be given. Therefore, patients with hypertension, arteriosclerosis, renal insufficiency and diabetes should take appropriate supplements of vitamin D and calcium and use corticosteroids with caution. 2. Induce or aggravate infection Corticosteroids have anti-inflammatory effects, but not antibacterial effects. They can reduce the body's ability to resist infection, reduce the body's disease resistance, and facilitate the growth, reproduction and spread of bacteria. Therefore, long-term use of corticosteroids may induce infection or cause the body's latent infection foci to expand or spread, and may also cause previously dormant tuberculosis foci to spread. During the medication process, attention should be paid to changes in the condition and whether there is any infection-inducing phenomenon, and anti-infection treatment should be given at the same time. 3. Induce or aggravate peptic ulcer In addition to hindering tissue repair and delaying tissue healing, glucocorticoids can also increase the secretion of gastric acid and pepsin, reduce gastric mucus secretion, reduce the resistance of gastric mucosa, induce or aggravate bleeding of gastric and duodenal ulcers, and even cause gastrointestinal perforation. 4. Neurological symptoms Agitation and insomnia may occur, and some patients may develop mental illness, and some patients may develop epileptic seizures. Therefore, it should not be used by patients with mental tendencies, mental illnesses and epilepsy. |
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