Is there any specific medicine to treat the sequelae of shingles?

I believe that in life, there is no disease more serious than skin disease. Skin diseases not only cause itching and swelling of the skin, but severe cases can cause blisters on the skin. Many men will find small pimples on their genitals. After the shingles are broken, they will ulcerate, cause local erosion, be contagious, itchy and stinging. Most of them are shingles caused by viral infection, which will also have sequelae or affect skin health. Severe cases can cause chronic herpes, leading to repeated recurrence of the disease. In order to avoid these sequelae, you can use drugs to treat it at ordinary times. There is no specific medicine for the treatment of shingles. They are all common antiviral and immunity-enhancing drugs, but you must pay attention to principles in treatment to speed up recovery.

1. Antiviral treatment

(1) Acyclovir is very effective against herpes simplex, but less sensitive to varicella-zoster. It is effective if used within 3 to 4 days of onset. In addition to oral administration (see the previous section), it can be slowly injected intravenously, 250 mg once every 5 to 12 hours, and one course of treatment is 5 days.

(2) Adenosine (Vira-A) and cytarabine (Ara-C) can prevent viral DNA synthesis and interfere with its replication. Administer within 1 week of onset. It can prevent new blisters and shorten the duration and severity of pain. It is mainly used for elderly and frail patients, but attention should be paid to the drug's damaging effects on the liver and bone marrow. The dosage of Vira-A is 10 mg/(kg·d), and that of Ara-C is 1.5 mg/(kg·d), both are added to 1000 ml of 5% glucose solution and injected intravenously for 5 consecutive days.

(3) Interferon: 1 to 3 million units per day. Intramuscular injection can interfere with the replication process of viral particles and prevent their proliferation. It has a better effect on elderly patients and critically ill patients.

2.Immune enhancement therapy

(1) Transfer factor: 2-4 ml subcutaneous injection in the axillary or groin area can quickly stop the appearance of new blisters, relieve pain, and gradually subside the inflammatory response. If necessary, inject again within 24 to 48 hours.

(2) Cimetidine (cimetidine): 800 mg/d, orally in 4 divided doses. This product acts as a histamine H2 receptor antagonist. Antagonize T suppressor cells to produce histamine-induced inhibitory factor, thereby enhancing the body's cellular immune function.

(3) Normal human immunoglobulin: 0.6-1.2 mg/(kg·d), intramuscular injection, twice a week.

complication

Severe cases may be complicated by pneumonia and meningitis.

Prognosis

The principles of Western medicine for the treatment of herpes zoster are antiviral, anti-inflammatory and analgesic, and prevention of secondary infection. Antiviral drugs include adenosine, acyclovir and interferon. Anti-inflammatory and analgesic drugs such as aspirin, vitamin B1, vitamin B12, etc. The local affected area can be applied with 2% gentian violet solution or compound Sanguisorba officinalis zinc oxide oil (raw Sanguisorba officinalis 10g, Lithospermum officinale 5g, borneol 2g, zinc oxide oil added to 100g). If there is secondary infection, neomycin ointment can be applied externally. If the eyes are affected, you can use herpes eye ointment. If necessary, transfer factor or immunoglobulin can be injected. In addition, the disease that causes herpes zoster should be identified and treated.