What is trilineage cytopenia?

The human body has many cells, and various cells are combined to form the bone marrow, human body, blood, secretions, etc. Among the many cells contained in the blood, tri-lineage blood cells are the most common. Tri-lineage blood cells are extremely prone to diseases, especially bone marrow diseases are difficult to treat, so people with tri-lineage blood cell diseases must pay attention to these to reduce the incidence.

Diseases that cause trilineage reduction include

1. Myelopoietic disorders (including myeloproliferation hypoplasia and ineffective bone marrow hematopoiesis), aplastic anemia, acute hematopoietic arrest, megaloblastic anemia, immune-related pancytopenia (IRP), hemophagocytic syndrome; thymoma, hyperthyroidism

2. Clonal proliferation diseases: Benign clonal proliferation diseases: paroxysmal nocturnal hemoglobinuria (PNH); Malignant clonal proliferation diseases: acute leukemia (AL), myelodysplastic syndrome (MDS), malignant histiocytosis, lymphoma bone marrow infiltration, hairy cell leukemia, multiple myeloma, primary macroglobulinemia, primary myelofibrosis, solid tumor bone marrow metastasis, bone marrow

Necrosis, some are non-clonal proliferative diseases, such as severe infection, hemoglobin S disease, etc.), low-proliferative chronic myeloid leukemia, peripheral consumption diseases: hypersplenism, systemic lupus erythematosus (some cases are bone marrow production disorders, etc.

In short, there are many diseases that cause a decrease in the three blood lines, but the most common blood diseases are aplastic anemia, MDS, immune-related pancytopenia, leukemia, myelofibrosis, etc.