What are the early symptoms of splenomegaly?

Everyone needs to pay attention to the symptoms of splenomegaly, because only by discovering these symptoms in time and taking timely treatment measures can the harm be effectively reduced. Mild enlargement can manifest as congestive heart failure, portal hypertension of cirrhosis and juvenile rheumatoid arthritis.

(1) Mild splenomegaly: When taking a deep breath, the lower edge of the spleen is 2 to 3 cm below the costal margin, which is mild splenomegaly. It can be seen in certain viral infections, bacterial infections, rickettsial infections, early schistosomiasis, congestive heart failure, portal hypertension due to cirrhosis, Hodgkin's disease, juvenile rheumatoid arthritis, systemic lupus erythematosus, tropical eosinophilia, idiopathic thrombocytopenic purpura, etc.

(2) Moderate splenomegaly: The lower edge extends 3 cm below the costal margin to the level of the navel, which is moderate enlargement. It can be seen in acute myeloid leukemia, acute lymphocytic leukemia, chronic hemolytic anemia, infectious mononucleosis, vitamin D deficiency, splenic amyloidosis, malignant lymphoma, Niemann-Pick disease, etc.

(3) Extreme splenomegaly: When the lower edge extends beyond the level of the umbilicus, it is called extreme splenomegaly or giant spleen. It can be seen in chronic myeloid leukemia, chronic malaria, late-stage schistosomiasis, banthalamosis, myelofibrosis, polycythemia vera, thalassemia, Gaucher disease, etc.

(4) Anemia, bleeding spots or ecchymoses: seen in hematologic splenomegaly, such as various types of leukemia, idiopathic thrombocytopenic purpura, etc.