Hemoglobin has a great impact on the human body. Low or high hemoglobin is an abnormal manifestation. At this time, some symptoms will appear, and the human body will begin to get sick and feel uncomfortable. At this time, you need to go to the hospital for a specific physical examination to prevent the body from having more serious diseases that we cannot discover. What exactly is hemoglobin? What role does hemoglobin play in the body? Below is a detailed introduction to the issue of hemoglobin. Hemoglobin is a protein (abbreviated as HB or HGB) responsible for carrying oxygen in higher organisms. It is the protein that makes blood red. Hemoglobin consists of four chains, two α chains and two β chains, each of which has a ring-shaped heme containing an iron atom. Oxygen is bound to iron atoms and transported in the blood. The characteristics of hemoglobin are: it easily combines with oxygen in places with high oxygen content; and it easily separates from oxygen in places with low oxygen content. This characteristic of hemoglobin enables red blood cells to transport oxygen. Hemoglobin (hemoglobin; haemoglobin; HB; HGB) Each hemoglobin molecule is composed of one molecule of globin and four molecules of ferrous heme. Each heme is composed of four pyrrole rings with an iron atom in the center of the ring. When the iron in hemoglobin is in a divalent state, it can reversibly bind to oxygen (oxyhemoglobin). If the iron is oxidized to a trivalent state, Hemoglobin is converted into methemoglobin and loses its oxygen-carrying capacity. Globin accounts for about 96% and hemoglobin accounts for 4%. Both α and β are similar to myoglobin, except that the peptide chains are slightly shorter: the α subunit is 141aa; the β subunit is 146aa. The α and β subunits face each other across a cavity. In mammals, hemoglobin accounts for 97% of the dry weight of red blood cells and 35% of the total weight. On average, each gram of hemoglobin can bind 1.34 ml of oxygen, which is 70 times the amount of dissolved oxygen in plasma. Under physiological conditions, about 1/120 of the human body's red blood cells die every day, and at the same time, another 1/120 of the red blood cells are produced, maintaining a dynamic balance between the production and death of red blood cells. This balance can be disrupted for a variety of reasons, resulting in a decrease or increase in the number of red blood cells and hemoglobin.Hemoglobin is an important component in human blood. No matter whether it is too high or too low, you should go to the hospital for a regular blood test in time to prevent any disease from being discovered in time. If you feel unwell, you should go to the hospital for a check-up in time. This is good for your health and prevents delays in treatment. |
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