Causes of abo hemolysis disease

Many people want to fully understand the cause of ABO hemorrhage disease, because the occurrence of such a disease will have a serious impact on the health of the body, especially when children have this disease, parents should pay more attention to it. In order not to affect the health of children, the following content gives a detailed introduction, you can fully understand it.

ABO hemolytic disease is the most common type of maternal-fetal blood type incompatibility hemolytic disease, which mainly occurs when the mother is O type and the fetus is A or B type. Other blood types are extremely rare. This disease is caused by the fetus receiving the mother's (through the placenta) homologous immune antibodies. The condition for the onset of the disease is that the mother has been stimulated by foreign antigens to produce corresponding immune antibodies. The antibodies produced by the mother enter the fetus through the placenta, and the fetus has immune sensitivity to these antibodies and becomes sick.

Causes

ABO hemolytic disease is the most common type of maternal-fetal blood type incompatibility hemolytic disease, which mainly occurs when the mother is O type and the fetus is A or B type. Other blood types are extremely rare. This disease is caused by the fetus receiving the mother's (through the placenta) homologous immune antibodies. The condition for the onset of the disease is that the mother has been stimulated by foreign antigens to produce corresponding immune antibodies. The antibodies produced by the mother enter the fetus through the placenta, and the fetus has immune sensitivity to these antibodies and becomes sick.

Epidemiology

ABO blood type incompatibility accounts for 20% to 25% of pregnancies, and ABO hemolytic disease occurs in only about 10% of them, that is, 2% to 2.5% of pregnancies will develop the disease. The incidence of RhD blood type incompatibility is 5%. The incidence rate of first pregnancy is 40% to 50%.

Through a comprehensive introduction to the causes of ABO hemorrhage disease, I believe that many parents of patients have already had a specific understanding. After fully understanding the causes of ABO hemorrhage disease, in order to prevent this disease from causing serious harm to the body, it is necessary to choose a large hospital as soon as possible and conduct comprehensive examinations and treatments to effectively control the disease as soon as possible.