Paget breast cancer malignancy degree

Paget's breast cancer is highly malignant and requires prompt medical treatment for surgery, radiotherapy and drug treatment. Paget's breast cancer is a special type of breast cancer characterized by eczematous lesions in the nipple and areola area, often accompanied by intraductal carcinoma or invasive carcinoma. Its malignancy is related to the extent of the lesion, whether it is accompanied by other types of breast cancer, and the patient's overall health.

1. Genetic factors: Some patients with Paget breast cancer may have BRCA1 or BRCA2 gene mutations, which increase the risk of breast cancer. It is recommended that people with a family history undergo genetic testing for early detection and intervention.

2. Environmental factors: Long-term exposure to chemical carcinogens, radiation or bad lifestyle habits such as smoking and drinking may increase the risk of disease. Reducing exposure to harmful environments and maintaining a healthy lifestyle can help reduce the risk.

3. Physiological factors: Physiological changes such as abnormal estrogen levels and breast tissue hyperplasia may promote the occurrence of Paget's breast cancer. Regular breast examinations, especially for menopausal women, can help detect lesions early.

4. Trauma: Trauma or chronic inflammation in the breast area may induce local tissue malignancy. Avoid trauma in the breast area and treat inflammatory lesions in a timely manner.

5. Pathological factors: Paget's breast cancer is often accompanied by intraductal carcinoma or invasive carcinoma, which are highly malignant. Early diagnosis and treatment are the key to improving survival rate.

Treatments include surgical removal of diseased tissue, radiotherapy to remove residual cancer cells, and drug therapy such as targeted therapy and chemotherapy. The surgical method can be mastectomy or breast-conserving surgery, radiotherapy can reduce the risk of recurrence, and drug therapy is selected according to the patient's specific situation. In terms of diet, it is recommended to consume more foods rich in antioxidants such as blueberries and green tea, and avoid high-fat and high-sugar diets. In terms of exercise, moderate aerobic exercise such as walking and swimming can help improve immunity.

Paget's breast cancer is highly malignant. Early diagnosis and comprehensive treatment are the key to improving prognosis. Patients should actively cooperate with doctors to develop personalized treatment plans and follow up regularly to monitor changes in the disease.