What causes pancreatic cancer

The causes of pancreatic cancer include genetic factors, environmental influences, physiological metabolic abnormalities, and certain disease-related risks. A variety of factors work together to lead to this malignancy. Understanding these specific causes can help us focus on prevention and early screening.

1. Genetic factors

Pancreatic cancer has a certain genetic tendency, and people with a family history of pancreatic cancer have a higher risk of the disease. Studies have shown that pancreatic cancer is related to certain gene mutations, such as BRCA1 and BRCA2. People with a family history are recommended to undergo regular pancreatic ultrasound examinations and cancer-related marker screening to detect potential dangers in a timely manner.

2. Environmental factors

Smoking, long-term alcohol abuse, and long-term high-fat, high-sugar diets are important risk factors for pancreatic cancer. Smokers can increase their risk of disease by 2-3 times, while drinking alcohol may cause chronic inflammation of the pancreas and increase the probability of cancer. To prevent it, you should avoid smoking, reduce alcohol intake, and choose light foods rich in dietary fiber, such as whole grains, vegetables, and fruits.

3. Chronic diseases and metabolic disorders

Chronic pancreatitis, diabetes and pancreatic cancer are closely related. Some long-term inflammation may cause pancreatic cell lesions and increase the risk of cancer. If you have been diagnosed with chronic pancreatitis or diabetes, you should closely monitor changes in your condition, have regular physical examinations, and take active control measures as directed by your doctor.

4. Pathological factors

Certain infections such as Helicobacter pylori infection or gastrointestinal dysfunction may indirectly induce the development of pancreatic cancer. Ageing and changes in male hormone levels may also increase the risk of cancer. It is recommended that people over 40 years old, especially men, establish a habit of health check-ups to detect suspicious symptoms early, such as persistent upper abdominal pain, jaundice, weight loss, etc.

5. Trauma

Although less common, physical damage to the pancreas is also thought to be a possible cause of pancreatic cancer. People with a history of pancreatic trauma or surgery should be carefully monitored for physical abnormalities during recovery from surgery.

Pancreatic cancer is the result of a combination of factors, but many of these risk factors can be avoided through active lifestyle adjustments. Prevention of pancreatic cancer should start with reducing smoking and drinking, improving diet, and managing diabetes. Regular physical examinations are the most effective way to detect early lesions, especially for those with a family history or other high-risk groups.