Which foods have the effect of preventing liver cancer? Eating more of these foods is beneficial to preventing liver cancer

The fruit raspberry can significantly inhibit the proliferation of liver cancer cells, weaken the expression of vascular endothelial growth factor in liver cancer cells, and enhance the expression of wild p53 tumor suppressor gene. This project successfully identified two specific protein targets of raspberry in preventing liver cancer growth for the first time at home and abroad, providing an important theoretical basis for fruits and vegetables to prevent primary liver cancer.

Raspberry, also known as raspberry, tray, and raspberry, is a perennial deciduous shrub of the genus Rubus in the Rosaceae family. There are more than 750 species. It is named raspberry because its fruit shape, color, and taste are similar to strawberries but it grows on trees. This fruit contains a large amount of anti-aging substances such as vitamin C, E, superoxide dismutase, and γ-aminobutyric acid, as well as anti-cancer substances such as tannic acid. The content of vitamin E and tannic acid is the highest among all fruits. In the United States, red raspberries are regarded as cancer killers and people praise them as "rubies".

In 2000, experts tried to mix tannic acid in raspberries with liver cancer cells and found that the former could significantly inhibit the growth of the latter. Later, experts focused their research on the medicinal value of natural plants and found that grapes and apples can prevent the proliferation of cancer cells.

With the support of the National Natural Science Foundation, the Ministry of Personnel's Returned Overseas Students Fund, and Heilongjiang Province's Science and Technology Research Fund, the expert group has in recent years carried out "Research on the Mechanism of Raspberry in Preventing and Inhibiting Liver Cancer" from the perspectives of medicine, nutrition, botany, cytology and molecular biology.

It is well known that oxidative damage to genetic material is one of the causes of most tumors. The results of the study showed that as the concentration of phytochemicals in raspberries increased, the ability to resist oxidative damage also increased. The inhibition rate of raspberry extracts at different concentrations on the liver cancer cell line HepG-2 showed a gradual increase, with the highest inhibition rate reaching about 90%. In a stable rat primary liver cancer model established using chemical toxins aflatoxin and diethylnitrosamine, as the concentration of raspberry extract increased, the tumor diameter on the liver of the experimental group rats became smaller, the number of tumors decreased, the tumor formation rate decreased, and the degree of nodules was reduced.

At the same time, proteomic research showed that there are two protein spots that are very likely to be the protein targets of raspberry in preventing liver cancer.

Experts have pointed out that currently, there are two synergistic risk factors that greatly increase the chance of liver cancer. One is chronic infection with the hepatitis B virus, and the other is chronic exposure to aflatoxin, a highly toxic liver toxin produced by mold that contaminates staple foods. One of the important ways to reduce the impact of these two carcinogenic factors is chemical prevention, that is, taking drugs or food supplements to offset the harm of aflatoxin. In the future, using phytochemicals extracted from raspberries, reasonably matching and forming preventive agents, will be very helpful in preventing the occurrence of liver cancer, inhibiting the development of liver cancer, and improving the survival rate of patients with this disease.

How to consume raspberries and other fruits properly?

Experts recommend: First, eat at least two kinds of fruits such as raspberries, grapes, apples or oranges every day. If you eat them with three or more vegetables such as cauliflower, tomatoes, carrots, etc., the effect will be better; second, after soaking and washing fruits such as raspberries, grapes, and apples, it is best to eat them whole without peeling them; third, people at high risk of liver cancer should consume no less than 200 grams of raspberries every day, and eat them between meals. The effect will be better if eaten with two other fruits and two vegetables.