How to treat the pain in the late stage of cervical cancer? How to relieve the pain in the late stage of cervical cancer?

In the late stage of cervical cancer, when the tumor compresses or erodes the ureter, the tube becomes narrow and blocked, leading to hydronephrosis, which manifests as low back pain or even severe pain, and further develops into renal failure, leading to uremia. If the tumor further spreads to the lymphatic metastasis, the lymphatic system will cause lymphatic obstruction, and reflux will further lead to lower limb edema and pain. So, what are the causes and hazards of pain in the late stage of cervical cancer?

Treatment of pain in advanced cervical cancer begins with assessment

The world-recognized method for assessing cervical cancer pain is the Numerical Rating System (NRS). The NRS uses numbers to indicate the degree of pain, which ranges from 0 to 10, with 0 being painless and 10 being unbearable severe pain. The commonly used method in clinical practice is to let the patient share the degree of pain themselves, which is simple and easy to implement.

When assessing cancer pain in patients with cervical cancer, the main principle for medical staff is to believe the patient's main complaint: since pain is a subjective feeling of the patient and lacks objective signs, pain is not only the body's physiological response to harmful stimuli, but also affected by mental and psychological factors. Therefore, pain assessment must believe the patient's main complaint, encourage the patient to fully describe the pain sensation and pain-related medical history, and encourage the patient to actively participate in pain assessment.

Three-step analgesia ladder for advanced cervical cancer pain

The three-step analgesia principle is that after correctly assessing the nature and cause of cancer pain, experts will classify it into three levels: mild, moderate, and severe according to the severity of pain in patients with advanced cervical cancer, and then choose different drugs based on this. Mild cancer pain is generally tolerable, and daily life and sleep are not affected. Non-steroidal anti-inflammatory analgesics represented by aspirin are used; if it develops into moderate and persistent pain, sleep will be disturbed and appetite will decrease, and weak opioids will become the first choice; for patients with severe pain who cannot tolerate severe pain, strong opioid preparations represented by morphine are needed.

Premature or excessive use of analgesics can bring unexpected adverse effects to patients, even aggravate the condition and shorten life. Therefore, under the guidance of medical staff, medication should be given according to the specific conditions of the patient, and less use can be made. Mixing practical analgesics can reduce drug resistance.

Overdose of painkillers is likely to cause drug resistance. For some cervical cancer patients who already have drug resistance, D-block is an exogenous differentiation inducer. By inducing differentiation and apoptosis, cancer cells not only undergo differentiation changes in morphology, but also in function, and eventually evolve cancer cells into normal cells, or even completely transform into normal cells. This phenomenon is called "reversal."