Skin symptoms caused by lymphoma

Lymphoma is a malignant tumor that mostly occurs in young and middle-aged people. The annual incidence in my country is as high as 20,000 to 30,000 people, and the mortality rate is quite high. The lymphatic system is part of the immune system, so people with poor immune systems are at special risk. We should pay attention to enhancing our immunity. So, what are the symptoms of lymphoma? What changes will occur in the skin?

Since lymphatic tissue is distributed throughout the body, the clinical manifestations of lymphoma vary greatly depending on the location and extent of the lesion. Primary lesions can be found in lymph nodes, as well as in organs other than lymph nodes, such as tonsils, nasopharynx, gastrointestinal tract, spleen, bones, and skin. Extranodal lesions are particularly common in non-Hodgkin's lymphoma. Disease metastasis can be from the primary site to adjacent lymph nodes in sequence, such as Hodgkin's disease, or it can skip adjacent lymph nodes and spread to distant lymph nodes, which is common in non-Hodgkin's lymphoma.

Symptoms of lymphoma include:

1. Systemic symptoms: Malignant lymphoma may cause systemic symptoms such as fever, itching, night sweats and weight loss before or at the same time as the discovery of lymph node enlargement.

2. Immune and blood system manifestations: 10% to 20% of patients may have anemia when diagnosed with malignant lymphoma. Some patients may have increased white blood cell count, thrombocytosis, and increased erythrocyte sedimentation rate. Some patients may have leukemoid reactions and a significant increase in neutrophils. The increase in lactate dehydrogenase is related to tumor load. Some patients, especially those in the late stage, show abnormal immune function. In B-cell NHL, different amounts of monoclonal immunoglobulins can be detected in the serum of some patients.

3. Skin lesions: Patients with malignant lymphoma may have a series of non-specific skin manifestations. The skin lesions are polymorphic, with erythema, blisters, erosions, etc. Patients with advanced malignant lymphoma have low immunity, and skin infections often ulcerate and exude for a long time, forming systemic scattered skin thickening and desquamation.