The main cause of pancreatic cancer

In life, cancer is a major killer. Many people who suffer from pancreatic cancer will develop a series of diseases in their bodies. Therefore, it is also very important to cure pancreatic cancer in time. Next, let's take a look at the causes of pancreatic cancer .

1. Smoking: This is one of the causes of pancreatic cancer. A large number of studies support the close connection between pancreatic cancer and smoking. Possible mechanisms of smoking causing pancreatic cancer: ① Smoking promotes the secretion of tobacco-specific N-nitrite, a carcinogen, into the bile duct, which then flows back into the pancreatic duct; ② The specific effect of tobacco-specific N-nitrite on the organ can flow into the pancreas with the blood. Experiments have confirmed that maintaining adequate folic acid and pyridoxal concentrations can reduce the risk of pancreatic cancer related to smoking.

2. Drinking: The latest research finds that although epidemiological studies do not support that drinking is the cause of pancreatic cancer, excessive drinking can increase the risk of pancreatic cancer.

3. Chronic pancreatitis: Most epidemiological and molecular epidemiological studies support that chronic pancreatitis can develop into pancreatic cancer. The FRIESS study showed that among 5,600 genes, 34 genes had reduced expression in patients with pancreatic cancer and chronic pancreatitis, 157 genes had increased expression in chronic pancreatitis, and 152 of them also had increased expression in pancreatic cancer. This study proved at the molecular level that there may be some connection between chronic pancreatitis and pancreatic cancer. Therefore, this is also an important factor in the cause of pancreatic cancer.

The above is a detailed description of the causes of pancreatic cancer. I hope it can help everyone understand the knowledge of pancreatic cancer and cure pancreatic cancer in time. If you have other questions about pancreatic cancer, you can contact our online experts to answer your questions.

For more information, please visit the pancreatic cancer disease special topic at http://www..com.cn/zhongliu/yxa/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.