Are there any side effects of taking pethidine?

Are there any side effects of taking pethidine?

Demerol is mainly used to deal with pain caused by various traumas, burns or scalds. It can effectively act as an anesthetic and relieve patients' pain. However, a small number of patients may experience some adverse reactions after the injection of Demerol, often accompanied by dizziness, headache, sweating, dry mouth and tongue. Severe cases may cause pupil dilation and hallucinations, and blood pressure function may also be affected. Therefore, the side effects of Demerol are relatively large.

Indications

1. Analgesia for various severe pains, such as trauma, burns, scalds, postoperative pain, etc.

2.Cardiac asthma.

3. Administer medication before anesthesia.

4. Severe visceral colic (biliary colic and renal colic need to be used in combination with atropine).

5. Used in combination with chlorpromazine, promethazine, etc. for artificial hibernation.

Dosage

1. [Oral] 50-100 mg each time. Maximum dose: 150 mg each time, 600 mg per day.

2. Subcutaneous injection or intramuscular injection: 25-100 mg each time, maximum dose: 150 mg each time, 600 mg per day. The interval between 2 doses of medication should not be less than 4 hours.

The scientific name of pethidine is pethidine, also known as meperidine, demerol, and meperidine hydrochloride. Its hydrochloride is a white, odorless, crystalline powder that is soluble in water and is generally prepared in the form of an injection. As a synthetic anesthetic drug, pethidine is widely used in clinical practice. Its effects and mechanisms on the human body are similar to those of morphine, but its analgesic and anesthetic effects are smaller, only equivalent to 1/10-1/8 of morphine, and the effect lasts about 2-4 hours. It mainly acts on the central nervous system and also has certain effects on cardiovascular and smooth muscles. The toxic and side effects are also relatively small. Symptoms such as nausea, vomiting, and constipation are all mild. The inhibitory effect on the respiratory system is weak, and problems such as difficulty breathing and overdose generally do not occur.

Precautions

1. It is less addictive than morphine, but continuous use can also cause addiction.

2. Adverse reactions include dizziness, headache, sweating, dry mouth, nausea, vomiting, etc. Overdose can cause mydriasis, convulsions, hallucinations, tachycardia, hypotension, respiratory depression, coma, etc.

3. It is not suitable for subcutaneous injection because it is irritating to the local area.

4. Use with caution in children. Children under 1 year old should generally not be given this drug intravenously or put into artificial hibernation.

5. It should not be used multiple times with promethazine, otherwise it may cause respiratory depression, shock and other adverse reactions.

6. Other precautions and contraindications are the same as morphine.

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