On which day does chickenpox feel the most itchy

Chickenpox is a very common disease. Many children will get it, and this disease has no age limit. Many adults may also suffer from this disease. After being infected, you will feel a rash all over your body, and sometimes it will feel very itchy. Most patients are infected due to respiratory tract infections, which will increase the difficulty of treatment.

The disease is caused by infection with the varicella-zoster virus (VZV). Varicella-zoster virus belongs to the Herpesviridae family. It is a double-stranded DNA virus with only one serotype. There are at least eight types of viral glycoproteins, which determine the pathogenicity and immunogenicity of the virus. The virus has very weak survival ability in the external environment, is not resistant to heat and acid, and can be inactivated by disinfectants such as ether. Humans are the only host of the virus, and patients are the only source of infection. The infectious period is generally from 1 to 2 days before the rash appears until the herpes is completely scabbed. Immunodeficient patients may be contagious throughout the course of the illness. Children may also develop chickenpox if they come into contact with someone with shingles, as the two have the same cause.

Chickenpox is highly contagious, and the main routes of transmission are respiratory droplets or direct contact. After the virus infects the human body, it first proliferates and replicates in the local lymph nodes in the nasopharynx for 4 to 6 days, then invades the blood and spreads throughout the body, causing lesions in various organs. The lesions of this disease are mainly in the spinous cell layer of the skin. The cells swell and degenerate to form cystic cells with eosinophilic inclusion bodies in the nucleus. Herpes is formed after cell lysis and infiltration of tissue fluid. The blister fluid contains large numbers of infectious virus particles. Blisters are also common on the mucosal surfaces of the oropharynx, respiratory tract, gastrointestinal tract, conjunctiva, and vagina.

People of any age can be infected with the varicella-zoster virus, with infants, preschoolers and school-age children being more likely to be infected, and infants under 6 months old being less likely to be infected. The spread of varicella among susceptible populations depends mainly on factors such as climate, population density and medical and health conditions.

Control the source of infection and isolate the child until all the rashes are scabbed over. Susceptible children who have been in contact should be quarantined for 3 weeks. For people with weakened immune function, those taking immunosuppressants, and pregnant women, if there is a history of exposure, immunoglobulin G or herpes zoster immune globulin can be used for intramuscular injection. The live attenuated varicella vaccine is the first human herpes virus vaccine approved for clinical use in many countries. Follow-up observations after vaccination found that the varicella vaccine has a good protection rate for recipients.