What are the histological classifications of lung cancer?

What are the histological classifications of lung cancer?

The main histological classifications of lung cancer include squamous cell carcinoma, adenocarcinoma, large cell carcinoma, small cell carcinoma, adenosquamous carcinoma, carcinoid, and bronchial adenocarcinoma.

1. Malignant epithelial tumors with squamous cell carcinoma, muscle keratinization, and intercellular bridges can be divided into well-differentiated squamous cell carcinoma, moderately differentiated squamous cell carcinoma, and poorly differentiated squamous cell carcinoma. There are many central types of squamous cell carcinoma. They can be easily biopsied as seen from the endoscope. The tumor is formed by large necrosis and cavitation, and sometimes there is obvious stromal lymphocyte infiltration.

2. Adenocarcinoma can be divided into four subtypes: alveolar adenocarcinoma, papillary adenocarcinoma, bronchioloalveolar cell carcinoma and solid carcinoma.

3. Large cell carcinoma, with large nuclei, prominent nucleoli, abundant cytoplasm, and clear cell boundaries, but without squamous cell carcinoma, adenocarcinoma, and small cell carcinoma. Large cells can be divided into giant cell carcinoma and clear cell carcinoma.

4. Small cell carcinoma can be divided into brome cell carcinoma, intermediate cell carcinoma and compound brome cell carcinoma.

5. Adenosquamous carcinoma, a cancer cell with both adenocarcinoma and squamous cell carcinoma components. Two characteristic cancer cells can be seen in the same cancer tissue.

6. Cancer is an endocrine cell tumor. Central type, polygonal cells, prominent nucleoli, rare nuclear division, regular nuclear size, mostly positive for silver staining, multiple tumors, highly malignant, small tumors, usually not accompanied by cancer syndrome, and few extrapulmonary metastases.

7. Bronchial adenocarcinoma, a typical bronchial gland salivary type, more than 80% of which are central type, can be divided into adenoid cystic carcinoma and mucoepidermoid carcinoma.