How to use medicine for gastric cancer? You can try these four medicines

Patients with gastric cancer need to be especially careful when taking medication. 5-Fluorouracil is a cell cycle-specific drug that has a killing effect on proliferating cells at all stages. Zimicycline, furanfluorouracil, doxorubicin, etc. are all helpful for the improvement of gastric cancer. You need to cooperate with the doctor to take the medication according to the dosage and choose a reasonable treatment plan according to the condition.

Everyone knows that if you are sick, you need to seek timely treatment. Drug treatment is very important, especially for serious diseases such as gastric cancer. In addition to surgical treatment, drugs are also needed for treatment. It is very important for patients to understand the use of drugs for gastric cancer. Otherwise, the drugs will not only be detrimental to the patient's condition, but also cause irritation to the body. So how to use drugs for gastric cancer?
1. 5-Fluorouracil was synthesized in 1957 by Duschkinsky and other ingredients. It is a pyrimidine anti-metabolite drug. 5-FU originally had no anti-cancer effect and needs to be converted into 5-fluoro-2-deoxyuridine monophosphate in the body to work. FDUMP inhibits thymidine nucleotide synthase, and then can inhibit uracil deoxynucleotide from becoming thymidine deoxynucleotide, which may affect the synthesis of DNA in cells.
This drug is cell cycle-specific and has a strong killing effect on proliferating cells at different stages. It can also help improve the G1/S boundary. The half-life is about 10-20 minutes, and it is metabolized in the liver. Its side effects are that it helps the bone marrow suppress the formation of white blood cells and reduce platelets. Generally, it will improve 2-3 weeks after stopping the drug. Patients may also experience gastrointestinal manifestations such as loss of appetite, nausea, vomiting, and diarrhea.
2. Ziromycin: In 1955, an antibiotic component with anti-tumor effect was extracted from the culture medium. This drug will be linked to DNA, which can depolymerize DNA, thereby inhibiting the replication of cell DNA. It is a non-specific drug for the cell cycle. This drug has a wide range of anti-cancer effects and is effective, but it is highly toxic. Side effects should not be ignored, such as bone marrow suppression, fewer white blood cells and platelets, and prolonged duration, which need to be slowly recovered after stopping the drug.
3. The effect of furanyl fluorouracil is also good: after taking the medicine, it will be absorbed by the human body in the jejunum and ileum, and enter the liver through the portal vein. In the liver cells, it is converted into 5-FU through the cytochrome P-450 microsomal enzyme system, and it can also be converted into 5-FU through the soluble enzymes of local tissues to play an effect. Therefore, the 5-FU that needs to be decomposed after FT-207 does not all reach the target tissue through the blood circulation, so the side effects are not great and the effect is very good.
FT-207 and uracil are taken in proportion to the condition of the disease, and the concentration of 5-FU in the tumor will suddenly increase, making the anti-cancer effect of FT-207 better. This synergistic effect is due to the increase in the phosphorylation effect of 5-FU into F-DUMP. The mixture of FT-207 and uracil is called UFT.
4. Adriamycin is also suitable for patients with gastric cancer: it is very similar to orthomycin. It has a good anti-cancer effect and a high therapeutic index. It is a non-specific drug for the cell cycle. It is absorbed by the body through liver metabolism. If liver function declines, the dose should be reduced. This product is very toxic to the heart, and the apparent toxicity is inseparable from the total dose. If the total dose is 400 mg/m2, it will threaten the heart and cause heart failure. It will also cause leukopenia and thrombocytopenia, and anemia.