Where is the most common site of osteosarcoma? What is the cause of osteosarcoma?

The knee joint is the most common site of osteosarcoma; the incidence rate of the femur, tibia, and humerus is also high; osteosarcoma can occur in the mandible, maxilla, spine and other parts, but the incidence rate is lower.

1. Knee joint <br/>Osteosarcoma is a primary malignant tumor of the bone. All bones may develop lesions, and the knee joint is the most common site of osteosarcoma. When osteosarcoma occurs in adolescents, the chance of lesions in the knee joint and surrounding areas is higher, often accompanied by joint pain, limited mobility and other symptoms.
2. Femur <br/>The bone is also prone to osteosarcoma, especially the lower end of the femur.
3. Tibia <br/>The chance of osteosarcoma in the tibia is lower than that in the knee joint and femur, but the incidence rate is also not low. Osteosarcoma is generally more likely to occur in the upper end of the tibia.
4. Humerus <br/>The humerus is also a high-incidence site for osteosarcoma. In addition, osteosarcoma may also occur in the mandible, maxilla, spine and other parts, but the incidence rate is relatively low.