What are the causes of colorectal cancer? Colorectal cancer is a very common malignant disease in life, and many factors in life are the causes of colorectal cancer . Let's take a look at how experts answer the question of the causes of colorectal cancer. Causes of colorectal cancer: 1. Genetic factors: About 1/4 of the families of colorectal cancer patients have a family history of cancer, and half of them also have digestive tract tumors. Due to the change of normal cell genes, cancer patients inherit a susceptibility through inheritance, and with certain stimulating factors, tissue cells grow rapidly and develop into cancer. Cell genetic genes mutate and become malignant cells with tumor genetic characteristics, showing familial cancer. 2. Dietary factors: A high-fat, high-meat, low-fiber diet is closely related to the occurrence of rectal cancer. A high-fat diet not only stimulates increased bile secretion, but also promotes the growth of certain anaerobic bacteria in the intestine. Once cholesterol and bile salts are decomposed by anaerobic bacteria to form unsaturated cholesterol, such as deoxycholic acid and lithocholic acid, they increase in the intestine. The latter two are carcinogens or co-carcinogens, and can therefore lead to the occurrence of colorectal cancer. 3. Chronic inflammatory stimulation: Chronic inflammatory stimulation can lead to the occurrence of rectal cancer. For example, schistosomiasis, amoebic dysentery, chronic nonspecific ulcerative colitis, chronic bacillary dysentery, etc. can cause cancer through granuloma, inflammatory and pseudopolyp stages. 4. Polyps: The incidence of colorectal cancer is closely related to polyps. Some people believe that rectal polyps are the precursors of cancer, especially familial multiple adenomatous polyposis, which is very likely to become cancerous; papillary adenomatous polyps also have a higher chance of becoming cancerous. 5. Other factors: It is closely related to mental factors, age, endocrine factors, environmental stress resistance, climatic factors, immune dysfunction and viral infection, but colorectal cancer can only occur under certain conditions. The above are the causes of colorectal cancer. Through the introduction of experts, I believe you have a certain understanding of the causes of colorectal cancer. If you have any questions about the causes of colorectal cancer, please consult our online experts. For more information, please visit the colorectal cancer disease special topic at http://www..com.cn/zhongliu/dca/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation. |
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