Can rabies vaccine be used after being frozen

Rabies vaccine is a vaccine that everyone is very familiar with, which is used to prevent rabies. There are many problems with rabies vaccines because the human body should be checked for its adaptability before injection. Some people may resist or react to rabies vaccine due to their physical problems. And the storage method of vaccines is also very important, so they should be frozen regularly. But can the rabies vaccine still be used after being frozen?

Rabies is an acute infectious disease of natural or animal origin caused by the rabies virus. It is widely prevalent, has an extremely high mortality rate, and poses a serious threat to people's lives and health. Rabies vaccine is a vaccine with a long history. The first person to produce rabies vaccine was Pasteur of France. The rabies vaccine currently produced in China is made by inoculating fixed rabies virus into primary hamster kidney cells. After cultivation, the venom is harvested, concentrated, purified, refined, and added with aluminum hydroxide adjuvant. After passing comprehensive testing, it becomes a vaccine for preventing rabies. There is only one serotype of rabies virus, and the antigenic properties of rabies virus are the same around the world. After vaccination with rabies vaccine, anti-rabies virus antibodies may appear in human blood. These antibodies can prevent the virus from spreading directly between cells and reduce the amount of virus proliferation. At the same time, they can also eliminate free rabies viruses and prevent the virus from reproducing and spreading, thereby preventing rabies. The storage temperature of rabies vaccine should be between 2 and 8 degrees. Therefore, refrigerated trucks are required for transportation and storage is required in refrigerators or ice boxes that meet temperature requirements. If the product is found to have clots that cannot be shaken apart or discoloration, or if the ampoule is cracked, or if the liquid vaccine has been frozen, it must not be used.

Precautions for rabies vaccination

1. During the vaccination period, you should be careful not to drink alcohol, strong tea, or coffee; also do not eat irritating foods such as peppers, onions, garlic, etc.

2. Try to avoid catching a cold, and avoid strenuous exercise or excessive fatigue.

3. If a pregnant woman is bitten, she should also receive the full course of rabies vaccination in a timely manner.

4. To get the rabies vaccine, you must go to a regular hospital or CDC with rescue equipment so that you can get timely rescue if an allergic reaction occurs.

5. If you find that the vaccine has clots that cannot be shaken apart, or is discolored, or the bottle has cracks, or the liquid vaccine has been frozen, do not inject it.

6. Vitamins and anti-infection drugs can be given at the same time as rabies vaccination. At the same time, to avoid immune interference, patients should try not to receive other vaccines during the rabies vaccination period.