Why does chickenpox itch

Chickenpox is mostly more common in children. If it occurs, you need to treat your baby in time, because this is mainly a disease caused by viral infection. You must find out the source of infection before you can treat it. Generally speaking, you must do relevant examinations as soon as the disease occurs, so that you can clarify the cause of the disease.

The disease is caused by infection with the varicella-zoster virus (VZV). Varicella-zoster virus belongs to the Herpesviridae family. It is a double-stranded DNA virus with only one serotype. There are at least eight types of viral glycoproteins, which determine the pathogenicity and immunogenicity of the virus. The virus has very weak survival ability in the external environment, is not resistant to heat and acid, and can be inactivated by disinfectants such as ether.

Humans are the only host of the virus, and patients are the only source of infection. The infectious period is generally from 1 to 2 days before the rash appears until the herpes is completely scabbed. Immunodeficient patients may be contagious throughout the course of the illness. Children may also develop chickenpox if they come into contact with someone with shingles, as the two have the same cause.

Chickenpox is highly contagious, and the main routes of transmission are respiratory droplets or direct contact. After the virus infects the human body, it first proliferates and replicates in the local lymph nodes in the nasopharynx for 4 to 6 days, then invades the blood and spreads throughout the body, causing lesions in various organs. The lesions of this disease are mainly in the spinous cell layer of the skin. The cells swell and degenerate to form cystic cells with eosinophilic inclusion bodies in the nucleus. Herpes is formed after cell lysis and infiltration of tissue fluid. The blister fluid contains large numbers of infectious virus particles. Blisters are also common on the mucosal surfaces of the oropharynx, respiratory tract, gastrointestinal tract, conjunctiva, and vagina.

People of any age can be infected with the varicella-zoster virus, with infants, preschoolers and school-age children being more likely to be infected, and infants under 6 months old being less likely to be infected. The spread of varicella among susceptible populations depends mainly on factors such as climate, population density and medical and health conditions.

1. Electron Microscopy

By taking fresh herpes fluid for electron microscopic examination, herpes virus particles can be seen, which can be quickly distinguished from smallpox virus.

2. Virus Isolation

Within 3 days of onset, herpes fluid was collected and inoculated into human embryo amniotic tissue, and the virus isolation positive rate was high.

3. Serological examination

The commonly used test is the complement fixation test. Complement fixation antibodies will appear in the serum of varicella patients 1 to 4 days after diagnosis, reach a peak in 2 to 6 weeks, and gradually decrease after 6 to 12 months. The antibody titer of double serum increases by more than 4 times. Indirect fluorescent antibody test

4. PCR method

The PCR method for detecting viral DNA in nasopharyngeal secretions is a sensitive and rapid means of early diagnosis.

5. Blood picture

The total white blood cell count is normal or slightly decreased, and the lymphocyte count is increased.